I guess I have been really lucky. The only sick I have had is self inflicted!!! we also bring Imodium, sinus, allergy, pepto, ect. little things like this so we don't have to go searching for it. plus the pepto stuff they had at the resort store was very expensive! bring your vitamins, take them. stay hydrated! Lysol is a very good idea. use hand wipes on the plane!! very germy there!!!! sounds as if a few people on here have had some major issues with ac. if you get sinus problems, breathing prob. whatever take their advice just to be safe. then go have fun!! because there sure is a lot of that to be found!